Publish in this journal
Journal Information
Share
Download PDF
More article options
ePub
Visits
...
Original article
Available online 13 June 2025
Influence of social factors in a cohort of ischemic heart disease: Insights from the RECORVAL registry
Influencia de los factores sociales en una cohorte de cardiopatía isquémica: perspectivas del registro RECORVAL
Visits
10
Jon Zubiaura,
Corresponding author
jonzubiaur5@gmail.com

Corresponding author.
, Raquel Pérez Barquína, Adrián Margarida de Castroa, Andrea Teira Calderónb, Fermín Sáinz Lasoa, Dae-Hyun Lee Hwanga, Tamara García-Camareroa, Gabriela Veigaa, Aritz Gil Ongaya, Celia Garilletia, Rigoberto Hernándeza, Sergio Barreraa, Víctor Fradejasa, Cristina Obregóna, José M. de la Torre Hernándeza
a Servicio de Cardiología, Hospital Universitario Marqués de Valdecilla, Instituto de Investigación Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Cantabria, Spain
b Servicio de Cardiología, Hospital Universitario y Politécnico La Fe, Valencia, Spain
This item has received
Received 10 February 2025. Accepted 19 May 2025
Article information
Abstract
Full Text
Bibliography
Download PDF
Statistics
Figures (3)
Show moreShow less
Tables (5)
Table 1. General and social characteristics of the population.
Tables
Table 2. Univariate and multivariate Cox proportional regression for the combinate endpoint.
Tables
Table 3. Univariate and multivariate Cox proportional regression for death.
Tables
Table 4. Comparison of basal characteristics between groups by self-management of treatment.
Tables
Table 5. Comparison of basal characteristics between groups by home internet access.
Tables
Show moreShow less
Additional material (1)
Abstract
Introduction and objectives

Cardiovascular disease accounts for a considerable proportion of both morbidity and mortality. In addition to well-established risk factors, some studies have identified a correlation between social determinants such as social support, income, and psychosocial factors and worse outcomes.

Methods

A prospective, single-centre observational study was conducted on patients diagnosed with coronary disease following coronary angiography. In addition to traditional risk factors, social determinants were collected via a researcher-administered questionnaire. Clinical events were prospectively recorded. A composite endpoint was defined as cardiovascular death, myocardial infarction (MI), or coronary revascularization. A multivariate Cox proportional hazards regression analysis was conducted using variables selected from the univariate analysis.

Results

A total of 2213 patients were followed for a median duration of 1461 days. The mean age of the cohort was 66.3 years; 23.5% were women, 27.8% had diabetes mellitus, and 10.4% had chronic kidney disease. During the follow-up period, there were 343 (15.5%) composite endpoint events, including 109 (4.9%) deaths, 85 (4%) cardiovascular deaths, 182 (8.2%) MI, 229 (10.3%) revascularizations, 70 (3.2%) strokes, and 129 (5.8%) clinically significant haemorrhages. The multivariate analysis revealed that 2 social variables were significantly associated with the composite endpoint: self-management of treatment (aHR, 0.61; 95%CI, 0.44–0.85; P<.01) and home Internet access (aHR, 0.73; 95%CI, 0.56–0.97; P=.013).

Conclusions

Certain social factors, such as self-management of treatment and internet access, are associated with a better prognosis in patients with ischemic heart disease. Identification of these patients would enable healthcare professionals to potentially improve prognosis.

Keywords:
Cardiovascular disease
Coronary artery disease
Heart disease risk factors
Social determinants of health
Resumen
Introducción y objetivos

La enfermedad cardiovascular es una de las principales causas de morbilidad y mortalidad. Además de los factores de riesgo conocidos, factores como el apoyo social, los ingresos y otros factores psicosociales se han asociado con un peor pronóstico.

Métodos

Realizamos un estudio observacional prospectivo, unicéntrico, en pacientes con enfermedad arterial coronaria tras una angiografía coronaria. Además de los factores de riesgo tradicionales, recogimos determinantes sociales mediante un cuestionario. Se realizó un seguimiento prospectivo de eventos clínicos. Definimos un criterio de valoración compuesto por muerte cardiovascular, infarto de miocardio (IM) o revascularización coronaria. Realizamos un análisis de regresión de Cox multivariante con las variables seleccionadas del análisis univariante.

Resultados

Se siguió a 2.213 pacientes durante una mediana de 1.461 días. Su edad media fue de 66,3 años; 23,5% eran mujeres, 27,8% tenían diabetes mellitus y 10,4% tenían enfermedad renal crónica. Durante el seguimiento, hubo 343 (15,5%) eventos del criterio compuesto, incluyendo 109 (4,9%) muertes, 85 (4%) muertes cardiovasculares, 182 (8,2%) IM, 229 (10,3%) revascularizaciones, 70 (3,2%) accidentes cerebrovasculares y 129 (5,8%) hemorragias. Las variables sociales asociadas con el criterio compuesto fueron la autogestión del tratamiento (aHR=0,61; IC95%: 0,44-0,85; p <0,01) y el acceso a internet (aHR=0,73; IC95%, 0,56-0,97; p=0,013).

Conclusiones

Ciertos factores sociales, como la autogestión del tratamiento y el acceso a internet, se asocian con un mejor pronóstico en pacientes con enfermedad coronaria isquémica. La identificación de estos pacientes permitiría a los profesionales sanitarios intervenir de manera dirigida, con el potencial de mejorar su pronóstico.

Palabras clave:
Enfermedad cardiovascular
Enfermedad arterial coronaria
Factores de riesgo cardiovascular
Determinantes sociales de salud

Article

These are the options to access the full texts of the publication REC: CardioClinics
Member
Socios SEC
Use datos de acceso a SEC en el menú Acceder.
Si es socio de la Sociedad Española de Cardiología y no puede acceder con sus claves, escriba a rec@cardioclinics.org.
Members of SEC
Use the Society's website login and password here.
If you are member of SEC and you have some problems with your login data, please contact with rec@cardioclinics.org.
Subscriber
Subscriber

If you already have your login data, please click here .

If you have forgotten your password you can you can recover it by clicking here and selecting the option “I have forgotten my password”
Subscribe
Subscribe to

REC: CardioClinics

Purchase
Purchase article

Purchasing article the PDF version will be downloaded

Price 19.34 €

Purchase now
Contact
Phone for subscriptions and reporting of errors
From Monday to Friday from 9 a.m. to 6 p.m. (GMT + 1) except for the months of July and August which will be from 9 a.m. to 3 p.m.
Calls from Spain
932 415 960
Calls from outside Spain
+34 932 415 960
Email
Idiomas
REC: CardioClinics
Article options
Tools
Supplemental materials
es en

¿Es usted profesional sanitario apto para prescribir o dispensar medicamentos?

Are you a health professional able to prescribe or dispense drugs?